Study Proves Differential Diagnosis of Fibrous Dysplasia of the Clivus

Dr. Badih Adada pic

Dr. Badih Adada
Image: my.clevelandclinic.org

A board-certified neurosurgeon working with Cleveland Clinic Florida, Dr. Badih Adada has performed complex brain surgeries for brain tumors, brain aneurysms, and vascular malformations of the brain. Previously an associate professor of neurosurgery at the University of Arkansas Medical School, Dr. Badih Adada was involved in a study that proved fibrous dysplasia could be differentially diagnosed.

Fibrous dysplasia is a skeletal disease that causes distortion and weakening of bones. Craniofacial involvement in the entity is recognized and can cause cosmetic deformity or neurovascular impingement. However, fibrous dysplasia of the clivus is not recognized and is rarely documented. Differentiating this specific disorder from other disease processes is vital for its proper management.

In this study, researchers studied fibrous dysplasia of the clivus with a goal to document its manifestations, outline a good management system, and increase awareness of the disease. Researchers reviewed a comprehensive database of previous patients and singled out patients diagnosed with fibrous dysplasia of the clivus. Eight patients were identified. Four of the patients showed no symptoms of the disease while the other four reported headaches as a symptom of the disease. The patients’ demographics, clinical results, radiological findings, and management were then reviewed.

Radiological findings were similar to the findings of hypointensity on T1- and T2- weighted magnetic resonance imaging studies. Four patients actually had a pathological confirmation.

Researchers concluded that fibrous dysplasia had to be given consideration in the differential diagnosis of lesions of the clivus as both radiological and clinical findings permitted a positive diagnosis.

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